Source: http://www.thehollywoodgossip.com/2013/01/kim-richards-sober-and-feeling-great/
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শুক্রবার, ২৫ জানুয়ারি, ২০১৩
বৃহস্পতিবার, ২৪ জানুয়ারি, ২০১৩
White House: Britain is stronger by being part of the EU
WASHINGTON (Reuters) - The White House said on Wednesday that the United States believes Britain is stronger by being a part of the European Union and the EU is stronger as a result of Britain's membership.
White House spokesman Jay Carney made the comments at a press briefing after British Prime Minister David Cameron promised Britons a vote on whether the country should stay in the EU or leave.
(Reporting by Jeff Mason; Editing by Sandra Maler)
Source: http://news.yahoo.com/white-house-britain-stronger-being-part-eu-181603692--business.html
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Genes provide clues to gender disparity in human hearts
Jan. 24, 2013 ? Healthy men and women show little difference in their hearts, except for small electrocardiographic disparities. But new genetic differences found by Washington University in St. Louis researchers in hearts with disease could ultimately lead to personalized treatment of various heart ailments.
Generally, men are more susceptible to developing atrial fibrillation, an irregular, rapid heartbeat that may lead to stroke, while women are more likely to develop long-QT syndrome, a rhythm disorder that can cause rapid heartbeats and sudden cardiac death.
While prior studies have clearly established differences in the development of heart disease between men and women, very few studies had looked at the molecular mechanisms behind those differences in human hearts.
Igor Efimov, PhD, the Lucy and Stanley Lopata Distinguished Professor of Biomedical Engineering in the School of Engineering & Applied Science at Washington University in St. Louis, and a former doctoral student, Christina Ambrosi, PhD, analyzed 34 human hearts looking for genetic differences that might explain gender differences in heart disease.
The team took advantage of the unique opportunity at the university to obtain failing human hearts at the time of transplantation from Barnes-Jewish Hospital and non-failing hearts unsuitable for transplantation from Mid-America Transplant Services, a St. Louis-based organ procurement service.
The team screened for 89 major genes in electrophysiology, ion channel subunits, calcium handling proteins and transcription factors important in cardiac conduction and in the development of arrhythmia and the left atria and ventricles in human hearts.
"What was striking in this study is that we expected very large gender differences in expression of genes in the ventricles, but we did not find such differences," says Efimov, also a professor of medicine, of radiology and of cell biology and physiology at Washington University School of Medicine. "Unexpectedly, we found huge gender differences in the atria."
The results showed that women with failing hearts have a weaker system of gene expression than men -- males showed overall higher expression levels of nearly all of the 89 genes than women.
Women showed particularly lower atrial expression levels of several important genes encoding for potassium channels, including Kv4.3, KChIP2, Kv1.5 and Kir3.1. In fact, the atria of women with heart disease had less than half of the KChIP2 mRNA than atria in men.
Results of the research were published in PLOS ONE.
Efimov says while there are still many questions that need to be answered to explain these molecular differences, one factor that could be contributing to the difference is estrogen.
"When women have the highest levels of estrogen, they are least vulnerable to arrhythmia -- women are protected by estrogen," he says. "But after menopause, women develop atrial fibrillation at the same rate as men. We don't understand this and need to study this in humans."
Another potential factor is circadian rhythm, Efimov says.
"Humans are much more likely to die suddenly from heart disease early in the morning, between 5-7 a.m.," he says. "In the cardiac system in mice, it has been shown that there is an oscillation of gene expression, so certain genes expressed at 5 a.m. could be different by threefold at 5 p.m."
Efimov says the study on human hearts is unique to Washington University, as much cardiac research elsewhere is done mostly in animal models. In the future, the team would like to expand the research into pediatric hearts, taking advantage of Washington University's leading pediatric heart transplant program to learn more about pediatric physiology.
Funding for this research was provided by the National Institutes of Health (R01-HL114395) and the National Heart, Lung, and Blood Institute (R-01-HL085369).
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The above story is reprinted from materials provided by Washington University in St. Louis. The original article was written by Beth Miller.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal Reference:
- Christina M. Ambrosi, Kathryn A. Yamada, Jeanne M. Nerbonne, Igor R. Efimov. Gender Differences in Electrophysiological Gene Expression in Failing and Non-Failing Human Hearts. PLoS ONE, 2013; 8 (1): e54635 DOI: 10.1371/journal.pone.0054635
Note: If no author is given, the source is cited instead.
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/pDQnFtrIs8U/130124150708.htm
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বুধবার, ২৩ জানুয়ারি, ২০১৩
Arab League encourages Israeli Arabs to get out the vote
Arab voter turnout in tomorrow?s elections is expected to drop below 50 percent ? one of the worst showings since 1949. Low turnout would diminish the Arab check on Israel's rightward shift.
Supporters of the Arab-led party the National Democratic Assembly attend a campaign rally in Nazareth, Israel's largest Arab town December 26. Disillusioned, disappointed and divided, Israeli Arab voters will traipse to the polls tomorrow in ever dwindling numbers.
Ammar Awad/Reuters
EnlargeBaqa al-Gharbiyya, Israel
On the eve of Israeli elections, the Arab League has taken the unusual step of intervening in Israeli politics, urging Israel?s Arab minority to flock to the polls. Otherwise, they warn, the country will be taken over by a far-right government that will increase discrimination toward Arab citizens and step up settlement expansion in the West Bank, where their Palestinian brethren have long sought a state of their own.
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Arabs make up a significantly larger voting bloc in Israel than Hispanics in the US ??14 percent of eligible voters, compared with 9 percent for Latinos.?But while US politicians conscientiously woo Latinos, Arabs enjoy no such courtship. Though their numbers have steadily grown?since being absorbed into Israel when it declared independence in 1948,?they have not been able to translate their numerical clout?into the political and economic equality they are entitled to on paper but rarely enjoy in practice.
They are underrepresented in academia and because they generally don?t serve in the army, they have difficulty getting jobs ??even sometimes at coffee shops ? and often end up doing manual labor. Nearly 6 in 10 live under the poverty line.?In the latest Knesset, Israeli Arabs held 17 of the 120 seats ? almost exactly proportionate to their share of eligible voters. But they were unable to block a raft of right-wing legislation that many saw as discriminatory against Arabs.???
?The last three years have been a nightmare for many Palestinians inside Israel,? says Honaida Ghanim, an Israeli citizen and director of the Palestinian Forum for Israeli Studies in Ramallah, West Bank. ?Almost 30 new laws and regulations were launched against them,? Ms. Ghanim adds.
Indeed, disillusionment with the political system is running high, as evidenced at a recent debate among eight Israeli Arab politicians, hosted by Al Qasami Academy in Baqa al-Gharbiyya.?
?What have you done?? asked one dismayed student, Malak, after all the candidates made their pitches for how they have helped or will help Arabs in Israel. ?I see you doing nothing.?
Arab voter turnout in tomorrow?s elections is expected to drop below 50 percent ? the worst showing since 1949, other than a 2001 boycott during the second intifada. At stake is the ability of the Arab community to find a unified voice to press for the rights they have been promised, as well as the ability and willingness of Israel to be faithful to its democratic ideals ? and make peace with those who were living here before the return of the Jewish diaspora.
?According to the public opinion polls that have been conducted in Israel, the radical right is expected to obtain a majority [of seats in the Knesset]," the Arab League said in a statement. "The radical right consists of right-wing groups that do not want peace; they refuse to accept the Other and they regard Israeli Arabs as a threat to the country.?
A call for unity
The fact that Israel has declared itself to be Jewish as well as democratic leaves Israeli Arabs unsure about their place in this society, and how best to?press for their rights.
?How can we exist in a state that defines itself as a Jewish state?? asked Mohammed Asawi, head of Al Qasami, as he welcomed the mainly Arab attendees to the debate. ?It?s a state where racism is growing.?
?You all know how the Nazis developed and how they controlled a complete country called Germany,? Mr. Asawi continued, implying a comparison with Israeli Jewish politicians. ?We need [members of parliament] that challenge racism. We have to develop our thinking toward liberating ourselves and others from racist attitudes. We have to distance ourselves from clans and tribes.?
But Arab politicians ? and voters ??are divided along many fault lines, which limits their collective bargaining power. Should they work with Israeli Jews, or stick to Arab-only parties? Should they work from within the parliament, and thus legitimize what many see as an unrepresentative system, or agitate for change outside of the Knesset? Should Arab politicians focus on economic issues like the astronomical rise in the cost of food and housing, or pursue more nationalist goals?
At the Al Qasami Academy debate, held Jan. 17, these divides were fully on display among the eight Israeli-Arab politicians. Some are already members of the Knesset; others are aspiring to be. One, a former prisoner, eschews the electoral process all together and chewed out a fellow debater, a member of the Knesset, for not delivering on his promise to fight for prisoner's rights ??a promise he had made while the accuser was serving 25 years in an Israeli jail. ?I never saw his face again,? the ex-prisoner said bitterly.
A professor who helped organize the event said he didn?t even believe in voting.
?If you are fighting now, how will you ever get unity?? asked the student, Malak, wearing a gold headscarf and an elegant turquoise dress.?They should be united for us to have a strong force,? she told the Monitor later. ?I think only united can they be strong, only united can they get us rights.?
Solidarity
Enter Asma Aghbarieh-Zahalka. She was the only woman on the debate stage, and the only Arab woman to head a political party ??no small feat in a patriarchal country where even Jewish women face glass ceilings in academia, business, and politics.
She started the party, Daam ??solidarity ??at age 22. Now, nearly two decades later, it has evolved from a nationalist party to one that seeks to bring Jews and Arabs together to work on social issues, such as workers? rights. Infused with new momentum after the Israeli social protests of 2011, Daam includes both Arabs and Jews at the top of its electoral list, and also seeks to work with Israeli Jews outside the party.
?Daam is trying to break the isolation that has been imposed on [Arabs in Israel],? Ms. Aghbarieh-Zahalka said during the debate. ?We have Jewish allies and they can affect the Israeli voters and politicians.?
One of these allies is Eran Brill, an activist with House of the People in Tel Aviv, who is 14th ?on Daam?s list. He notes that that's "largely symbolic," since Daam is unlikely to get more than the minimum three votes, meaning only the party's top three candidates would get a seat in the Knesset.?
"I became more and more fascinated by her very clear and brave political ideas; not least important is the fact that their basic values is people,? Mr. Brill says.
Improving social equality for both Arabs and Jews, Aghbarieh-Zahalka suggests, is part and parcel of solving the political problem.
"In my view this poverty, unemployment is connected to the political issues. All political ailments stem from social issues," she said during the debate. "When we are exploited socially we are not capable of helping others. You have to empower yourself to empower others, therefore both issues connect."
Many Israeli Arab politicians focus on the?nakba, or catastrophe, of Israel?s declaration of independence 65 years ago, at which time at least 700,000 Palestinians either fled or were forced from their homes ??many ending up outside Israel?s borders and unable to return. But Aghbarieh-Zahalka argues that while such important history should not be forgotten, it is more profitable to focus on the socioeconomic problems of today.
?80 percent of Arab women do not work ??this is a catastrophe,? she says over lunch after the debate, calling them victims of both Israeli discrimination and the neo-liberal economy.
?The occupation is deepening, the settlements are deepening, and the despair is deepening between Arabs and Jews. We feel there is a very huge need for an alternative,? Aghbarieh-Zahalka says.
?Arabs and Jews on the same list, with an Arab on top ??this is a dramatic change in Israel. It?s a new start for the relationship between Arabs and Jews.?
So far, Daam hasn?t managed to win the 2 percent threshold of votes necessary for entering the Knesset. But Aghbarieh-Zahalka, who has waited all these years for a seat in the Knesset, says they?re closer than ever. In the meantime, she?s patiently wooing voters ? in Hebrew and Arabic.?
* Chelsea B. Sheasley contributed reporting.
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L&T ad: when health insurance truly takes on your burden | Firstpost
Here?s a story of a man who bought a medical insurance policy. He thought, in an age when medical and hospitalisation costs can cripple your bank balance, it was the prudent decision to make
The consumer buys a policy, feeling better for the investment, feeling gratified that he has done the responsible thing.
A year later, he is unwell and his GP advises a number of tests. The results force the GP to advise hospitalisation and a procedure.
AFP
The consumer is not worried about the attendant costs; after all, he has invested, sensibly, in a policy just for a day like this.
The consumer seems to have no concern for worry. He has his policy documents, a card which seems to allow him to be admitted to a hospital without the payment of deposit, and so on.
Then the problem hits him. The hospital asks him to pay a deposit as the insurance company hasn?t approved of his claim yet. The consumer contacts his agent, the company concerned, and so on, to no avail.
Finally, the consumer pays the deposit, clears the bill and attempts to recover his expenses from the insurance company after discharge from the hospital.
Who hasn?t heard a story like this one?
L&T Insurance has. And they?ve decided, with their communications partner Salt Brand Solutions, that there?s a business opportunity in promising the consumer that their commitments and promises are just that ? commitments and promises.
Here?s a look at one of the TVCs from the campaign they?ve created to hit home the point.
The film begins with a mother telling her son that, if he ate his green vegetables, he would come first in class. The son immediately asks her if she would say the same thing to him ? in writing.
The crux of the commercial is to highlight the fact that there is a difference between just being ?assured? something verbally and the same assurance being made in writing ? which is what L&T Insurance says that they will do.
The film is clear on specifics:
That the company will respond in 6 hours
That if the company does not respond in 6 hours, they will be liable to pay a penalty and, finally,
That L&T will commit to this in writing
In a cluttered environment, with competing insurance companies making similar claims and similar ?promises?, what this commercial does is to say that, all things being the same, their promise is different.
They?ll keep it.
Source: http://www.firstpost.com/business/lt-ad-when-health-insurance-truly-takes-on-your-burden-597699.html
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